Pain is a general term that describes uncomfortable sensations in the body. It stems from the activation of the nervous system. Pain can range from annoying to debilitating, and it can feel like a sharp stabbing or a dull ache. Pain can also be described as throbbing, stinging, sore, and pinching. There are two main types of OTC pain medicines: acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin, naproxen (Aleve), and ibuprofen (Advil, Motrin) are examples of OTC NSAIDs. If OTC medicines don't relieve your pain, your doctor may prescribe something stronger.

You can choose between two main types of OTC fever reducers: acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include ibuprofen, aspirin, and naproxen. In general, no particular one of these fever-reducing drugs is better than the others.